Vidalista 80 mg can be taken with or without food. A high-fat meal may delay the onset of action but does not affect the overall effectiveness of the medication. Tadalafil in Vidalista 80 mg inhibits the enzyme phosphodiesterase type 5 (PDE5). This inhibition increases levels of cyclic guanosine monophosphate (cGMP), which relaxes smooth muscles in the blood vessels of the pill. This relaxation improves blood flow, helping to achieve and maintain an erection during sexual stimulation. Consult your healthcare provider if you have heart disease, high or low blood pressure, or a history of stroke, as Tadalafil can affect blood pressure. https://www.onemedz.com/product/vidalista-80-mg/