CDC is an effector function of IgG and IgM antibodies. When these antibodies bind to surface antigens, CDC is triggered and initiates the formation of membrane attack complex (MAC) and, hence target cell lysis.
One of the most researched Fc-mediated antibody effector functions is complement-dependent cytotoxicity (CDC), which weighs heavily on successful therapeutic interventions. We are dedicated to developing and facilitating the field of CDC enhanced antibodies, the key engine for therapeutic antibodies. We have a team of experts who have the most advanced knowledge of CDC enhancement technology. Our proprietary CDC+ antibody platform allows antibody conversion with limited or no chance to mutate into other potent cytotoxic antibodies, thus accelerating your research on different diseases.